Search on: NUCLEIC ACIDS, PEPTIDE 
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Descriptor English:   Peptide Nucleic Acids 
Descriptor Spanish:   Ácidos Nucleicos de Péptidos 
Descriptor Portuguese:   Ácidos Nucleicos Peptídicos 
Synonyms English:   Acids, Peptide Nucleic
Nucleic Acids, Peptide  
Tree Number:   D13.695.578.424.550
Definition English:   DNA analogs containing neutral amide backbone linkages composed of aminoethyl glycine units instead of the usual phosphodiester linkage of deoxyribose groups. Peptide nucleic acids have high biological stability and higher affinity for complementary DNA or RNA sequences than analogous DNA oligomers. 
History Note English:   99 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   33847 
Unique Identifier:   D020135 

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